Annotation Detail
Information
- Associated Genes
- HLA-DPB1
- Associated Variants
-
HLA-DQB2 c.98-309T>C
(
ENST00000411527.5,
ENST00000435145.6,
ENST00000437316.7 )
HLA-DPA1 c.*115T>C ( ENST00000419277.5, ENST00000692443.1 )
HLA-DPB1 c.*550A>G ( ENST00000416804.2, ENST00000428835.6, ENST00000418931.7 )
HLA-DQB2 c.98-309T>C ( ENST00000411527.5, ENST00000435145.6, ENST00000437316.7 )
HLA-DPA1 c.*115T>C ( ENST00000419277.5, ENST00000692443.1 )
HLA-DPB1 c.*550A>G ( ENST00000416804.2, ENST00000418931.7, ENST00000428835.6 ) - Associated Disease
- hepatitis B
- Source Database
- DisGeNET
- Description
- In addition, Uygurs have higher frequencies of HLA-DP/DQ protective alleles (72.5% for rs3077, 76.6% for rs9277535 and 26.8% for rs7453920) than Tibetans (51.7% for rs3077, 52.5% for rs9277535 and 18.5% for rs7453920)(all P < 0.05), and a lower prevalence of HBV infection as previously reported.
- Pubmed
- 25041342
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.132334436375453
- Year of publication
- 2014
Drugs