Annotation Detail

Information
Associated Genes
GBA1
Associated Variants
GBA1 MUTATION
GBA1 MUTATION
Associated Disease
Impaired cognition
Source Database
DisGeNET
Description
The GBA-associated PD patients compared with non-mutation PD patients, although younger and with an earlier age at onset, show (1) a more rapid disease progression of motor impairment and cognitive decline and (2) reduced survival rates.
Pubmed
25448271
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00162865123248182
Drugs