Annotation Detail
Information
- Associated Genes
- TNF
- Associated Variants
-
IL10 c.*452A>G
(
ENST00000659642.2,
ENST00000423557.1,
ENST00000664374.2,
ENST00000471071.2,
ENST00000659065.2 )
IL12B c.89-432G>A ( ENST00000231228.3, ENST00000696750.1 )
IL12B c.1-405G>T ( ENST00000231228.3, ENST00000696750.1 )
TNF c.187-122A>G ( ENST00000449264.3, ENST00000699334.1 )
IL10 c.*452A>G ( ENST00000423557.1, ENST00000471071.2, ENST00000659065.2, ENST00000659642.2, ENST00000664374.2 )
IL12B c.89-432G>A ( ENST00000231228.3, ENST00000696750.1 )
IL12B c.1-405G>T ( ENST00000231228.3, ENST00000696750.1 )
TNF c.187-122A>G ( ENST00000449264.3, ENST00000699334.1 ) - Associated Disease
- tuberculosis
- Source Database
- DisGeNET
- Description
- The variant of the TNFA gene at rs3093662, the IL12 gene at rs3213094 and rs3212220 and the IL10 gene at rs3024498 did show a strong indication to be of relevance to the immunity to tuberculosis.
- Pubmed
- 21463712
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0606658665622547
- Year of publication
- 2011
Drugs