Annotation Detail
Information
- Associated Genes
- ATP6AP2
- Associated Variants
-
ATP6AP2 MUTATION
ATP6AP2 MUTATION
NC_000017.11:g.63476833T>A
AGT c.-30-3484G>A ( ENST00000679957.1, ENST00000681269.1, ENST00000680783.1, ENST00000679684.1 )
rs2968915
NC_000017.11:g.63476833T>A
AGT c.-30-3484G>A ( ENST00000679684.1, ENST00000679957.1, ENST00000680783.1, ENST00000681269.1 )
rs2968915 - Associated Disease
- Hypertensive disease
- Source Database
- DisGeNET
- Description
- Four polymorphisms, located in the ACE (rs4291), angiotensinogen (rs5049) and (pro)renin receptor (rs2968915; rs5981008) genes were significantly associated with hypertension in two vascular disease populations of CAD (EUROPA) and cerebrovascular disease (PROGRESS; n = 3571).
- Pubmed
- 21157371
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00508145069940506
- Year of publication
- 2011
Drugs