Annotation Detail

Information
Associated Genes
ATM
Associated Variants
ATM MUTATION
ATM MUTATION
Associated Disease
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
Source Database
DisGeNET
Description
Together these findings define a synergistic function of ATM and CyclinD1 in pre-GC B-cell proliferation and lymphomagenesis and provide a prototypic animal model to study the pathogenesis of human MCL.
Pubmed
25676421
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree,CLINVAR,ORPHANET
DisGENET score for the Gene Disease association
0.246243163057847
Drugs