Annotation Detail

Information
Associated Genes
OGG1
Associated Variants
OGG1 c.948+613A>G, CAMK1 c.*110T>C ( ENST00000302008.12, ENST00000302036.12, ENST00000352937.6, ENST00000383826.9, ENST00000449570.6, ENST00000707074.1, ENST00000256460.8 )
OGG1 c.948+613A>G, CAMK1 c.*110T>C ( ENST00000302008.12, ENST00000302036.12, ENST00000352937.6, ENST00000383826.9, ENST00000449570.6, ENST00000707074.1, ENST00000256460.8 )
Associated Disease
Ewings sarcoma-primitive neuroectodermal tumor (PNET)
Source Database
DisGeNET
Description
However, after correcting for multiple comparisons, only the interaction between high trichloroethylene levels and OGG1 rs293795 significantly increased the risk of childhood M/PNET risk (OR = 9.24, 95% CI: 2.24, 38.24, Q = 0.04).
Pubmed
22389292
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2012
Drugs