Annotation Detail

Information
Associated Genes
YWHAE
Associated Variants
YWHAE MUTATION
YWHAE MUTATION
Associated Disease
Clear cell sarcoma of kidney
Source Database
DisGeNET
Description
Cyclin D1 overexpression in CCSK is not contingent on YWHAE-FAM22 translocation, and cyclin D1 inhibition may potentially be explored as a targeted therapeutic strategy in CCSK.
Pubmed
25751590
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
10
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs