Annotation Detail

Information
Associated Genes
EGFR
Associated Variants
rs2910164
rs2910164
Associated Disease
psoriasis
Source Database
DisGeNET
Description
These findings indicate that the rs2910164G allele in miR-146a weakens its suppression on the proliferation of keratinocytes probably through the decreased inhibition of the target gene, EGFR, which may account for the increased risk of psoriasis in this study population.
Pubmed
25209759
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Year of publication
2014
Drugs