Annotation Detail
Information
- Associated Genes
- NOD2
- Associated Variants
-
CLEC16A c.2641+18780G>A
(
ENST00000703130.1,
ENST00000409790.6 )
CLEC16A c.2641+18780G>A ( ENST00000409790.6, ENST00000703130.1 ) - Associated Disease
- Diabetes
- Source Database
- DisGeNET
- Description
- The effect of rs2903692 previously described in diabetes was observed specifically for Crohn's disease (CD) patients lacking the main susceptibility factor described to date, that is, three polymorphisms within another pattern recognition gene, NOD2/CARD15 (NOD2(-) vs NOD2(+) CD patients, G vs A: P=0.008; OR (95% CI)=1.54 (1.10-2.15); NOD2(-) CD patients vs controls: P=0.008; OR (95% CI)=1.37 (1.08-1.73)).
- Pubmed
- 19337309
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2009
Drugs