Annotation Detail

Information
Associated Genes
CLEC16A
Associated Variants
NC_000016.10:g.10877045G>A
CIITA p.Gly501Ala (p.G501A) ( ENST00000618327.4, ENST00000324288.14, ENST00000381835.9 )
CLEC16A c.2641+18780G>A ( ENST00000703130.1, ENST00000409790.6 )
CLEC16A c.2642-10916G>A ( ENST00000409790.6, ENST00000703130.1 )
NC_000016.10:g.10877045G>A
CIITA p.Gly501Ala (p.G501A) ( ENST00000324288.14, ENST00000381835.9, ENST00000618327.4 )
CLEC16A c.2641+18780G>A ( ENST00000409790.6, ENST00000703130.1 )
CLEC16A c.2642-10916G>A ( ENST00000409790.6, ENST00000703130.1 )
Associated Disease
rheumatoid arthritis
Source Database
DisGeNET
Description
The effect of the MHC2TA rs3087456G/rs4774C haplotype on RA susceptibility was confirmed, and the haplotype was found to be in negative linkage disequilibrium with the CLEC16A rs2903692A/rs6498169A haplotype.
Pubmed
19221398
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00554838957344497
Year of publication
2010
Drugs