Annotation Detail

Information
Associated Genes
BUB1B
Associated Variants
BUB1B p.Arg550Gln (p.R550Q) ( ENST00000287598.11, ENST00000412359.7 )
BUB1B p.Arg814His (p.R814H) ( ENST00000287598.11, ENST00000412359.7 )
BUB1B p.Leu844Phe (p.L844F) ( ENST00000287598.11, ENST00000412359.7 )
BUB1B p.Ile909Thr (p.I909T) ( ENST00000412359.7, ENST00000441369.6, ENST00000287598.11, ENST00000453867.7 )
BUB1B p.Gln921His (p.Q921H) ( ENST00000412359.7, ENST00000441369.6, ENST00000453867.7, ENST00000287598.11 )
BUB1B p.Leu1012Pro (p.L1012P) ( ENST00000558658.6, ENST00000453867.7, ENST00000287598.11, ENST00000412359.7, ENST00000441369.6 )
BUB1B p.Arg550Gln (p.R550Q) ( ENST00000287598.11, ENST00000412359.7 )
BUB1B p.Arg814His (p.R814H) ( ENST00000287598.11, ENST00000412359.7 )
BUB1B p.Leu844Phe (p.L844F) ( ENST00000287598.11, ENST00000412359.7 )
BUB1B p.Ile909Thr (p.I909T) ( ENST00000287598.11, ENST00000412359.7, ENST00000441369.6, ENST00000453867.7 )
BUB1B p.Gln921His (p.Q921H) ( ENST00000287598.11, ENST00000412359.7, ENST00000441369.6, ENST00000453867.7 )
BUB1B p.Leu1012Pro (p.L1012P) ( ENST00000287598.11, ENST00000412359.7, ENST00000441369.6, ENST00000453867.7, ENST00000558658.6 )
Associated Disease
mosaic variegated aneuploidy syndrome
Source Database
DisGeNET
Description
Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B.
Pubmed
15475955
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.561900093104562
Year of publication
2004
Drugs