Annotation Detail

Information
Associated Genes
LEP
Associated Variants
LEP p.Asn103Lys (p.N103K) ( ENST00000308868.5 )
LEP p.Asn103Lys (p.N103K) ( ENST00000308868.5 )
LEP p.Asn103= (p.N103=) ( ENST00000308868.5 )
LEP p.Asn103Lys (p.N103K) ( ENST00000308868.5 )
LEP p.Asn103Lys (p.N103K) ( ENST00000308868.5 )
LEP p.Asn103= (p.N103=) ( ENST00000308868.5 )
Associated Disease
obesity
Source Database
DisGeNET
Description
Severe Early-Onset Obesity Due to Bioinactive Leptin Caused by a p.N103K Mutation in the Leptin Gene.
Pubmed
26186301
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.44
Year of publication
2015
Drugs