Annotation Detail

Information
Associated Genes
VHL
Associated Variants
VHL p.Arg200Trp (p.R200W) ( ENST00000256474.3, ENST00000345392.3, ENST00000696143.2, ENST00000696153.1, ENST00000713811.1, ENST00000713812.1, ENST00000713815.1, ENST00000713982.1 )
VHL p.Arg200Trp (p.R200W) ( ENST00000256474.3, ENST00000345392.3, ENST00000696143.2, ENST00000696153.1, ENST00000713811.1, ENST00000713812.1, ENST00000713815.1, ENST00000713982.1 )
Associated Disease
Von Hippel-Lindau syndrome
Source Database
DisGeNET
Description
We evaluated the role of VHL in 8 children with a history of polycythemia and an elevated serum Epo level and found 3 different germline VHL mutations in 4 of them.
Pubmed
12393546
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.658392405606355
Year of publication
2003
Drugs