Annotation Detail

Information
Associated Genes
DHCR7
Associated Variants
DHCR7 MUTATION
DHCR7 MUTATION
DHCR7 p.His119Leu (p.H119L) ( ENST00000683714.1, ENST00000682708.1, ENST00000685320.1, ENST00000355527.8, ENST00000683287.1, ENST00000527316.6, ENST00000407721.6, ENST00000682880.1, ENST00000526780.6 )
DHCR7 p.His119Leu (p.H119L) ( ENST00000355527.8, ENST00000407721.6, ENST00000526780.6, ENST00000527316.6, ENST00000682708.1, ENST00000682880.1, ENST00000683287.1, ENST00000683714.1, ENST00000685320.1 )
Associated Disease
Smith-Lemli-Opitz syndrome
Source Database
DisGeNET
Description
Novel mutations in the 7-dehydrocholesterol reductase gene of 13 patients with Smith--Lemli--Opitz syndrome.
Pubmed
11427181
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.610363549988277
Year of publication
2001
Drugs