Annotation Detail

Information
Associated Genes
WFS1
Associated Variants
WFS1 p.Pro504Leu (p.P504L) ( ENST00000226760.5, ENST00000503569.5, ENST00000506362.2, ENST00000673991.1, ENST00000682275.1, ENST00000684087.1 )
WFS1 p.Arg818Cys (p.R818C) ( ENST00000226760.5, ENST00000503569.5, ENST00000506362.2, ENST00000673991.1, ENST00000682275.1, ENST00000684087.1 )
WFS1 p.Pro504Leu (p.P504L) ( ENST00000226760.5, ENST00000503569.5, ENST00000506362.2, ENST00000673991.1, ENST00000682275.1, ENST00000684087.1 )
WFS1 p.Arg818Cys (p.R818C) ( ENST00000226760.5, ENST00000503569.5, ENST00000506362.2, ENST00000673991.1, ENST00000682275.1, ENST00000684087.1 )
Associated Disease
Wolfram syndrome
Source Database
DisGeNET
Description
Presence of a major WFS1 mutation in Spanish Wolfram syndrome pedigrees.
Pubmed
11161832
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.62611927926214
Year of publication
2001
Drugs