Annotation Detail
Information
- Associated Genes
- PECAM1
- Associated Variants
- PECAM1 MUTATION
- Associated Disease
- Solid tumour
- Source Database
- DisGeNET
- Description
- Growth of solid tumors was significantly inhibited in animals treated with KPLK up to 21 days, tumor weights were decreased, and the expression of angiogenesis marker CD31 was downregulated; meanwhile, the apoptosis-related protein casspase-3 was upregulated.
- Pubmed
- 25125500
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 12
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs