Annotation Detail

Information
Associated Genes
PARP1
Associated Variants
PARP1 MUTATION
PARP1 MUTATION
Associated Disease
Solid tumour
Source Database
DisGeNET
Description
Olaparib (AZD-2281, Ku-0059436) is an orally bioavailable and well-tolerated poly(ADP-ribose) polymerase (PARP) inhibitor currently under investigation in patients with solid tumors.
Pubmed
25483710
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00217153497664243
Drugs