Annotation Detail

Information
Associated Genes
XRCC1
Associated Variants
XRCC1 MUTATION
XRCC1 MUTATION
Associated Disease
Conventional (Clear Cell) Renal Cell Carcinoma
Source Database
DisGeNET
Description
The TRACK mouse ccRCC model with constitutively active HIF1α but not HIF2α expressed in proximal tubules develops RCC.
Pubmed
24916472
Section of the abstract supporting the evidence
KEY MESSAGES
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00515739556952576
Drugs