Annotation Detail

Information
Associated Genes
MDM2
Associated Variants
MDM2 MUTATION
MDM2 MUTATION
Associated Disease
Squamous cell carcinoma of esophagus
Source Database
DisGeNET
Description
In this study, we examined the expression of GASC1 and certain GASC1-targeted genes (KLF4, MYC, SOX2, PPARG, MDM2, and NANOG) and identified a three-gene prognostic signature (PPARG, MDM2, and NANOG), using risk scores based on immunohistochemical analyses of 149 tumor specimens from patients with esophageal squamous cell carcinoma (ESCC).
Pubmed
25220908
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00298586059288334
Drugs