Annotation Detail

Information
Associated Genes
PRNP
Associated Variants
PRNP p.Glu200Lys (p.E200K) ( ENST00000379440.9, ENST00000424424.2, ENST00000430350.2, ENST00000457586.2 )
PRNP p.Glu200Lys (p.E200K) ( ENST00000379440.9, ENST00000424424.2, ENST00000430350.2, ENST00000457586.2 )
Associated Disease
Creutzfeldt-Jakob disease
Source Database
DisGeNET
Description
Slovakia is characterised by an unusually high number of patients affected by genetic Creutzfeldt-Jakob disease (CJD) with E200K mutation at the PRNP gene.
Pubmed
22026293
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.858675488785102
Year of publication
2011
Drugs