Annotation Detail
Information
- Associated Genes
- SOAT1
- Associated Variants
-
SOAT1 MUTATION
SOAT1 MUTATION - Associated Disease
- T-cell adult acute lymphoblastic leukemia
- Source Database
- DisGeNET
- Description
- A frequently affected pathway was the JAK/STAT pathway (18%) and a significant proportion of T-ALL patients harboured mutations in epigenetic regulators (33%), both predominantly found in the unfavourable subgroup of early T-ALL.
- Pubmed
- 25595890
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs