Annotation Detail

Information
Associated Genes
PRNP
Associated Variants
PRNP p.Glu200Lys (p.E200K) ( ENST00000379440.9, ENST00000424424.2, ENST00000430350.2, ENST00000457586.2 )
PRNP p.Glu200Lys (p.E200K) ( ENST00000379440.9, ENST00000424424.2, ENST00000430350.2, ENST00000457586.2 )
Associated Disease
Prion Diseases
Source Database
DisGeNET
Description
Creutzfeldt-Jakob disease (CJD) in Libyan Jews, linked to the E200K mutation in PRNP (E200KCJD), is the most prevalent of the inherited prion diseases.
Pubmed
11259483
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.481088376032419
Year of publication
2001
Drugs