Annotation Detail

Information
Associated Genes
FGFR3
Associated Variants
FGFR3 p.Ala393Glu (p.A393E) ( ENST00000352904.6, ENST00000412135.7, ENST00000440486.8, ENST00000481110.7, ENST00000340107.9 )
FGFR3 p.Ala393Glu (p.A393E) ( ENST00000340107.9, ENST00000352904.6, ENST00000412135.7, ENST00000481110.7, ENST00000440486.8 )
Associated Disease
acanthosis nigricans
Source Database
DisGeNET
Description
All three patients with the crouzonoid phenotype and acanthosis nigricans had the same mutation in exon 10 of FGFR3 (Ala391Glu).
Pubmed
10541159
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0144261453069126
Year of publication
1999
Drugs