Annotation Detail

Information
Associated Genes
FGFR3
Associated Variants
FGFR3 p.Ala393Glu (p.A393E) ( ENST00000352904.6, ENST00000412135.7, ENST00000440486.8, ENST00000481110.7, ENST00000340107.9 )
FGFR3 p.Ala393Glu (p.A393E) ( ENST00000340107.9, ENST00000352904.6, ENST00000412135.7, ENST00000481110.7, ENST00000440486.8 )
Associated Disease
achondroplasia
Source Database
DisGeNET
Description
Subtle radiographic findings of achondroplasia in patients with Crouzon syndrome with acanthosis nigricans due to an Ala391Glu substitution in FGFR3.
Pubmed
11426459
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.621035659391194
Year of publication
2001
Drugs