Annotation Detail

Information
Associated Genes
NR1I2
Associated Variants
NR1I2 MUTATION
NR1I2 MUTATION
Associated Disease
Metastatic melanoma
Source Database
DisGeNET
Description
The present finding uncovers a novel role of MDA-9/syntenin as an important TF·FVIIa·Xa/PAR-1-regulated gene that initiates a signaling circuit essential for cell motility and invasion of metastatic melanoma.
Pubmed
25505176
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs