Annotation Detail

Information
Associated Genes
GJB2
Associated Variants
GJB2 p.Asp179Tyr (p.D179Y) ( ENST00000382844.2, ENST00000382848.5 )
GJB2 p.Asp179Asn (p.D179N) ( ENST00000382848.5, ENST00000382844.2 )
GJB2 p.Asp179Tyr (p.D179Y) ( ENST00000382844.2, ENST00000382848.5 )
GJB2 p.Asp179Asn (p.D179N) ( ENST00000382844.2, ENST00000382848.5 )
Associated Disease
Hearing Loss, Mixed Conductive-Sensorineural
Source Database
DisGeNET
Description
A novel dominant missense mutation--D179N--in the GJB2 gene (Connexin 26) associated with non-syndromic hearing loss.
Pubmed
12786758
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0646031655551122
Year of publication
2003
Drugs