Annotation Detail

Information
Associated Genes
GJB2
Associated Variants
GJB2 p.Asp50Tyr (p.D50Y) ( ENST00000382844.2, ENST00000382848.5 )
GJB2 p.Asp50Asn (p.D50N) ( ENST00000382848.5, ENST00000382844.2 )
GJB2 p.Asp50Tyr (p.D50Y) ( ENST00000382844.2, ENST00000382848.5 )
GJB2 p.Asp50Asn (p.D50N) ( ENST00000382844.2, ENST00000382848.5 )
Associated Disease
Senter syndrome
Source Database
DisGeNET
Description
Dandy-Walker malformation in patients with KID syndrome associated with a heterozygote mutation (p.Asp50Asn) in the GJB2 gene encoding connexin 26.
Pubmed
19793313
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.328414698034489
Year of publication
2009
Drugs