Annotation Detail

Information
Associated Genes
GJB2
Associated Variants
GJB2 p.Asp50Tyr (p.D50Y) ( ENST00000382844.2, ENST00000382848.5 )
GJB2 p.Asp50Asn (p.D50N) ( ENST00000382848.5, ENST00000382844.2 )
GJB2 p.Ser17Phe (p.S17F) ( ENST00000382848.5, ENST00000382844.2 )
GJB2 p.Ser17Cys (p.S17C) ( ENST00000382848.5, ENST00000382844.2 )
GJB2 p.Asp50Tyr (p.D50Y) ( ENST00000382844.2, ENST00000382848.5 )
GJB2 p.Asp50Asn (p.D50N) ( ENST00000382844.2, ENST00000382848.5 )
GJB2 p.Ser17Phe (p.S17F) ( ENST00000382844.2, ENST00000382848.5 )
GJB2 p.Ser17Cys (p.S17C) ( ENST00000382844.2, ENST00000382848.5 )
Associated Disease
Senter syndrome
Source Database
DisGeNET
Description
Missense mutations in GJB2 encoding connexin-26 cause the ectodermal dysplasia keratitis-ichthyosis-deafness syndrome.
Pubmed
11912510
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.328414698034489
Year of publication
2002
Drugs