Annotation Detail

Information
Associated Genes
KCNH2
Associated Variants
KCNH2 p.Ile593Arg (p.I593R) ( ENST00000262186.10, ENST00000330883.9, ENST00000713701.1, ENST00000713710.1 )
KCNH2 p.Ile593Thr (p.I593T) ( ENST00000262186.10, ENST00000330883.9, ENST00000713701.1, ENST00000713710.1 )
KCNH2 p.Ile593Lys (p.I593K) ( ENST00000262186.10, ENST00000330883.9, ENST00000713701.1, ENST00000713710.1 )
KCNH2 p.Ile593Arg (p.I593R) ( ENST00000262186.10, ENST00000330883.9, ENST00000713701.1, ENST00000713710.1 )
KCNH2 p.Ile593Thr (p.I593T) ( ENST00000262186.10, ENST00000330883.9, ENST00000713701.1, ENST00000713710.1 )
KCNH2 p.Ile593Lys (p.I593K) ( ENST00000262186.10, ENST00000330883.9, ENST00000713701.1, ENST00000713710.1 )
Associated Disease
long QT syndrome 2
Source Database
DisGeNET
Description
Missense mutation in the pore region of HERG causes familial long QT syndrome.
Pubmed
8635257
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.360814325616241
Year of publication
1996
Drugs