Annotation Detail

Information
Associated Genes
LMNA
Associated Variants
LMNA p.Arg471Gly (p.R471G) ( ENST00000448611.6, ENST00000676385.2, ENST00000504687.7, ENST00000368300.9, ENST00000682650.1, ENST00000368299.7, ENST00000361308.9, ENST00000683032.1, ENST00000473598.6, ENST00000368297.5, ENST00000675939.1, ENST00000675667.1, ENST00000677389.1, ENST00000368301.6 )
LMNA p.Arg471Cys (p.R471C) ( ENST00000368297.5, ENST00000473598.6, ENST00000683032.1, ENST00000677389.1, ENST00000368301.6, ENST00000675939.1, ENST00000675667.1, ENST00000676385.2, ENST00000368300.9, ENST00000682650.1, ENST00000504687.7, ENST00000448611.6, ENST00000361308.9, ENST00000368299.7 )
LMNA p.Arg471Gly (p.R471G) ( ENST00000361308.9, ENST00000368297.5, ENST00000368299.7, ENST00000368300.9, ENST00000368301.6, ENST00000448611.6, ENST00000473598.6, ENST00000504687.7, ENST00000675667.1, ENST00000675939.1, ENST00000676385.2, ENST00000677389.1, ENST00000682650.1, ENST00000683032.1 )
LMNA p.Arg471Cys (p.R471C) ( ENST00000361308.9, ENST00000368297.5, ENST00000368299.7, ENST00000368300.9, ENST00000368301.6, ENST00000448611.6, ENST00000473598.6, ENST00000504687.7, ENST00000675667.1, ENST00000675939.1, ENST00000676385.2, ENST00000677389.1, ENST00000682650.1, ENST00000683032.1 )
Associated Disease
familial partial lipodystrophy
Source Database
DisGeNET
Description
The heterozygous LMNA mutation p.R471G causes a variable phenotype with features of two types of familial partial lipodystrophy.
Pubmed
18041775
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.157432691085282
Year of publication
2007
Drugs