Annotation Detail

Information
Associated Genes
LMNA
Associated Variants
LMNA p.Arg60Gly (p.R60G) ( ENST00000675939.1, ENST00000675667.1, ENST00000368301.6, ENST00000677389.1, ENST00000683032.1, ENST00000368299.7, ENST00000361308.9, ENST00000368300.9, ENST00000682650.1, ENST00000676385.2 )
LMNA p.Arg60Cys (p.R60C) ( ENST00000675667.1, ENST00000675939.1, ENST00000677389.1, ENST00000368301.6, ENST00000683032.1, ENST00000361308.9, ENST00000368299.7, ENST00000676385.2, ENST00000368300.9, ENST00000682650.1 )
LMNA p.Arg60Gly (p.R60G) ( ENST00000361308.9, ENST00000368299.7, ENST00000368300.9, ENST00000368301.6, ENST00000675667.1, ENST00000675939.1, ENST00000676385.2, ENST00000677389.1, ENST00000682650.1, ENST00000683032.1 )
LMNA p.Arg60Cys (p.R60C) ( ENST00000361308.9, ENST00000368299.7, ENST00000368300.9, ENST00000368301.6, ENST00000675667.1, ENST00000675939.1, ENST00000676385.2, ENST00000677389.1, ENST00000682650.1, ENST00000683032.1 )
Associated Disease
Familial Partial Lipodystrophy, Type 2
Source Database
DisGeNET
Description
Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease.
Pubmed
10580070
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.361900093104562
Year of publication
1999
Drugs