Annotation Detail

Information
Associated Genes
SLC6A2
Associated Variants
SLC6A2 MUTATION
SLC6A2 MUTATION
Associated Disease
Carcinoma breast stage IV
Source Database
DisGeNET
Description
Using the NET1 gene as an example, we show that the PR can dictate alternative promoter usage leading to the upregulation of an isoform that may play a role in metastatic breast cancer.
Pubmed
24897521
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs