Annotation Detail
Information
- Associated Genes
- BCR
- Associated Variants
-
BCR MUTATION
BCR MUTATION - Associated Disease
- Virchow's node (disorder)
- Source Database
- DisGeNET
- Description
- Our findings implicate STAT3 as a critical signaling node in BCR-ABL1 kinase-independent TKI resistance, and suggest that BP-5-087 has clinical utility for treating malignancies characterized by STAT3 activation.
- Pubmed
- 25134459
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs