Annotation Detail
Information
- Associated Genes
- TERT
- Associated Variants
-
TERT c.1573+4881A>G
(
ENST00000310581.10,
ENST00000334602.10 )
rs4977756
TERT c.1573+4881A>G ( ENST00000310581.10, ENST00000334602.10 )
rs4977756 - Associated Disease
- adenocarcinoma
- Source Database
- DisGeNET
- Description
- Two glioma risk variants, TERT rs2853676 and CDKN2BAS1 rs4977756, which are located in regions previously associated with lung cancer, were associated with increased risk of adenocarcinoma (OR = 1.16; 95% CI = 1.10 to 1.22; P = 1.1×10(-8)) and squamous cell carcinoma (OR = 1.13; CI = 1.07 to 1.19; P = 2.5×10(-5)), respectively.
- Pubmed
- 24681604
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0115300422808758
- Year of publication
- 2014
Drugs