Annotation Detail
Information
- Associated Genes
- TERT
- Associated Variants
-
TERT c.-245T>C
TERT c.-245T>C - Associated Disease
- Recurrent tumor
- Source Database
- DisGeNET
- Description
- Our data showed that a common polymorphism rs2853669, within a preexisting Ets2 binding site in the TERT promoter, acts as a modifier of the effect of the mutations on survival and tumor recurrence.
- Pubmed
- 24101484
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
- Year of publication
- 2013
Drugs