Annotation Detail

Information
Associated Genes
IL10RB
Associated Variants
IL10RB MUTATION
IL10RB MUTATION
IFNAR2-IL10RB p.Lys267Glu (p.K267E), IL10RB p.Lys47Glu (p.K47E) ( ENST00000290200.7, ENST00000609556.3, ENST00000637650.2, ENST00000433395.7 )
IFNAR2-IL10RB p.Lys267Glu (p.K267E), IL10RB p.Lys47Glu (p.K47E) ( ENST00000290200.7, ENST00000609556.3, ENST00000637650.2, ENST00000433395.7 )
Associated Disease
hepatitis B
Source Database
DisGeNET
Description
Furthermore, AA genotype of IL10RB-K47E was found to be significantly decreased in chronic HBV patients compared with individuals with self-limited HBV infection (P = 0.006, P(c)=  0.018 and OR = 0.45).
Pubmed
23745570
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.120814325616241
Year of publication
2013
Drugs