Annotation Detail
Information
- Associated Genes
- VCAM1
- Associated Variants
-
ICAM1 c.332-3499C>G
(
ENST00000264832.8,
ENST00000423829.2 )
VCAM1 c.929-458C>T ( ENST00000294728.7, ENST00000370119.8, ENST00000347652.6, ENST00000370115.1 )
ICAM1 c.332-3499C>G ( ENST00000264832.8, ENST00000423829.2 )
VCAM1 c.929-458C>T ( ENST00000294728.7, ENST00000347652.6, ENST00000370115.1, ENST00000370119.8 ) - Associated Disease
- Cardiovascular Diseases
- Source Database
- DisGeNET
- Description
- Of the 170 SNPs tested, multiplicative interactions between well-water arsenic and two SNPs, rs281432 in ICAM1 (padj = 0.0002) and rs3176867 in VCAM1 (padj = 0.035), were significant for CVD after adjustment for multiple testing.
- Pubmed
- 25575156
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.129172941823938
- Year of publication
- 2015
Drugs