Annotation Detail

Information
Associated Genes
PRX
Associated Variants
PRX p.Arg291Ter (p.R291*) ( ENST00000291825.11, ENST00000324001.8, ENST00000673881.1, ENST00000674005.2, ENST00000674773.1 )
PRX p.Arg291= (p.R291=) ( ENST00000291825.11, ENST00000324001.8, ENST00000673881.1, ENST00000674005.2, ENST00000674773.1 )
PRX p.Arg291Ter (p.R291*) ( ENST00000291825.11, ENST00000324001.8, ENST00000673881.1, ENST00000674005.2, ENST00000674773.1 )
PRX p.Arg291= (p.R291=) ( ENST00000291825.11, ENST00000324001.8, ENST00000673881.1, ENST00000674005.2, ENST00000674773.1 )
Associated Disease
Charcot-Marie-Tooth disease
Source Database
DisGeNET
Description
After characterizing the human PRX gene, we identified a nonsense R196X mutation in the Lebanese family which cosegregated with CMT.
Pubmed
11157804
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00943445217435406
Year of publication
2001
Drugs