Annotation Detail
Information
- Associated Genes
- CYP3A4
- Associated Variants
-
CYP21A2 p.Val282Met (p.V282M)
(
ENST00000435122.3,
ENST00000644719.2 )
CYP21A2 p.Val282Leu (p.V282L) ( ENST00000435122.3, ENST00000644719.2 )
CYP21A2 p.Val282Leu (p.V282L) ( ENST00000435122.3, ENST00000644719.2 )
CYP3A5 c.219-237A>G ( ENST00000222982.8, ENST00000439761.3 )
CYP3A4 c.-392G>A
CYP21A2 p.Val282Met (p.V282M) ( ENST00000435122.3, ENST00000644719.2 )
CYP21A2 p.Val282Leu (p.V282L) ( ENST00000435122.3, ENST00000644719.2 )
CYP21A2 p.Val282Leu (p.V282L) ( ENST00000435122.3, ENST00000644719.2 )
CYP3A5 c.219-237A>G ( ENST00000222982.8, ENST00000439761.3 )
CYP3A4 c.-392G>A - Associated Disease
- Hypertensive disease
- Source Database
- DisGeNET
- Description
- The CYP3A5 genotype was related with blood pressure in the general population, but the effect on the risk for hypertension in pregnancy has not been evaluated.We compared the allele and genotype frequencies of three functional SNPs in the CYP3A5 (rs776746), CYP3A4 (rs2740574), and CYP21A2 (rs6471) genes between pregnant women who developed hypertension (n = 250) or who remained normotensive (control group, n = 250).
- Pubmed
- 20617557
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00845830529620761
- Year of publication
- 2010
Drugs