Annotation Detail

Information
Associated Genes
CYP3A4
Associated Variants
CYP3A4 c.-392G>A
CYP3A4 c.-392G>A
Associated Disease
Carcinogenesis
Source Database
DisGeNET
Description
CYP3A4 encodes a key enzyme in oestrogen metabolism and our finding between rs2740574 and risk of ovarian cancer suggests that this pathway may be involved in ovarian carcinogenesis.
Pubmed
19127255
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00298586059288334
Year of publication
2009
Drugs