Annotation Detail
Information
- Associated Genes
- CYP3A4
- Associated Variants
-
CYP3A4 c.-392G>A
CYP3A4 c.-392G>A - Associated Disease
- Malignant neoplasm of ovary
- Source Database
- DisGeNET
- Description
- CYP3A4 encodes a key enzyme in oestrogen metabolism and our finding between rs2740574 and risk of ovarian cancer suggests that this pathway may be involved in ovarian carcinogenesis.
- Pubmed
- 19127255
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0073725378078864
- Year of publication
- 2009
Drugs