Annotation Detail

Information
Associated Genes
TERC
Associated Variants
TERC MUTATION
TERC MUTATION
Associated Disease
dyskeratosis congenita
Source Database
DisGeNET
Description
Genotype-phenotype correlations show genes responsible for X-linked (DKC1) and severe recessive childhood dyskeratosis congenita, typically with associated mucocutaneous features, and others (TERC and TERT) for more subtle presentation as telomeropathy in adults, in which multiorgan failure may be prominent.
Pubmed
25237198
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD,LHGDN,ORPHANET
DisGENET score for the Gene Disease association
0.271772137858252
Drugs