Annotation Detail

Information
Associated Genes
EPHX2
Associated Variants
TERT c.1574-3777G>T ( ENST00000310581.10, ENST00000334602.10 )
rs2741354
TERT c.1574-3777G>T ( ENST00000310581.10, ENST00000334602.10 )
rs2741354
Associated Disease
Malignant neoplasm of lung
Source Database
DisGeNET
Description
We identified one novel variant at the level corrected for multiple comparisons (rs2741354 in EPHX2 at 8q21.1 with p value = 7.4 × 10(-6)), and confirmed the associations between TERT (rs2736100) and the HLA region and lung cancer risk.
Pubmed
23370545
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00263847385068233
Year of publication
2013
Drugs