Annotation Detail
Information
- Associated Genes
- CLPTM1L
- Associated Variants
-
TERT c.1574-3777G>T
(
ENST00000310581.10,
ENST00000334602.10 )
TERT c.1573+4881A>G ( ENST00000310581.10, ENST00000334602.10 )
CLPTM1L c.1316-153G>A ( ENST00000320895.10, ENST00000507807.3, ENST00000630539.1 )
CLPTM1L c.264-739G>T ( ENST00000320895.10, ENST00000630539.1 )
TERT c.1574-3777G>T ( ENST00000310581.10, ENST00000334602.10 )
TERT c.1573+4881A>G ( ENST00000310581.10, ENST00000334602.10 )
CLPTM1L c.1316-153G>A ( ENST00000320895.10, ENST00000507807.3, ENST00000630539.1 )
CLPTM1L c.264-739G>T ( ENST00000320895.10, ENST00000630539.1 ) - Associated Disease
- nicotine dependence
- Source Database
- DisGeNET
- Description
- Gene variations rs2736100 and rs2853676 in TERT and rs401681 and rs31489 in CLPTM1L had significant direct associations on lung adenocarcinoma without indirect effects through nicotine dependence.
- Pubmed
- 25233467
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2014
Drugs