Annotation Detail

Information
Associated Genes
CLPTM1L
Associated Variants
TERT c.1574-3777G>T ( ENST00000310581.10, ENST00000334602.10 )
TERT c.1574-3777G>T ( ENST00000310581.10, ENST00000334602.10 )
Associated Disease
Adenocarcinoma of lung (disorder)
Source Database
DisGeNET
Description
A recent genome-wide association study of lung cancer among never-smoking females in Asia demonstrated that the rs2736100 polymorphism in the TERT-CLPTM1L locus on chromosome 5p15.33 was strongly and significantly associated with risk of adenocarcinoma of the lung.
Pubmed
23555636
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.243452799466923
Year of publication
2013
Drugs