Annotation Detail
Information
- Associated Genes
- GRK4
- Associated Variants
-
GRK4 MUTATION
GRK4 MUTATION - Associated Disease
- Renal sclerosis with hypertension
- Source Database
- DisGeNET
- Description
- The therapeutic importance of the GRK4 single nucleotide polymorphisms (SNPs) was emphasised in the African American Study of Kidney Disease (AASK) where African-Americans with hypertensive nephrosclerosis were randomised to receive amlodipine, ramipril or metoprolol.
- Pubmed
- 25775155
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 9
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs