Annotation Detail
Information
- Associated Genes
- TERT
- Associated Variants
-
TERT c.1574-3777G>T
(
ENST00000310581.10,
ENST00000334602.10 )
TERT c.-1382T>C
TERT c.1574-3777G>T ( ENST00000310581.10, ENST00000334602.10 )
TERT c.-1382T>C - Associated Disease
- Leukemia, Lymphocytic, Acute, L1
- Source Database
- DisGeNET
- Description
- Our findings suggested that TERT promoter rs2735940 polymorphism may affect the TERT activity, and rs2736100 may be associated with telomere function, and thus, it is a potential biomarker for genetic susceptibility to ALL in Chinese children.
- Pubmed
- 23066086
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
- Year of publication
- 2013
Drugs