Annotation Detail
Information
- Associated Genes
- GPX1
- Associated Variants
-
GPX1 MUTATION
GPX1 MUTATION - Associated Disease
- Sepsis
- Source Database
- DisGeNET
- Description
- Evaluating the subgroup of 293 ICU patients with sepsis, a pooled analysis including two genetic variants GPx1 and SOD2 (47C>T SNP, rs4880; protein variant in MnSOD: Ala-9Val) showed a significant difference in relation to progression to septic shock.
- Pubmed
- 25497738
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs