Annotation Detail
Information
- Associated Genes
- P2RX7
- Associated Variants
-
P2RX7 MUTATION
P2RX7 MUTATION - Associated Disease
- Sepsis
- Source Database
- DisGeNET
- Description
- Mice lacking P2X7 had increased susceptibility to polymicrobial sepsis, which was rescued by Tfh cell depletion or administration of purified IgM.
- Pubmed
- 25464855
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs