Annotation Detail

Information
Associated Genes
TNNI3
Associated Variants
TNNI3 p.Asn185Lys (p.N185K) ( ENST00000344887.10, ENST00000588882.1, ENST00000665070.1, ENST00000714236.1, ENST00000714237.1, ENST00000714238.1, ENST00000714240.1 )
TNNI3 p.Lys36Gln (p.K36Q) ( ENST00000344887.10, ENST00000665070.1, ENST00000714236.1, ENST00000714237.1, ENST00000714238.1 )
TNNI3 p.Asn185Lys (p.N185K) ( ENST00000344887.10, ENST00000588882.1, ENST00000665070.1, ENST00000714236.1, ENST00000714237.1, ENST00000714238.1, ENST00000714240.1 )
TNNI3 p.Lys36Gln (p.K36Q) ( ENST00000344887.10, ENST00000665070.1, ENST00000714236.1, ENST00000714237.1, ENST00000714238.1 )
Associated Disease
Cardiomyopathy, Familial Idiopathic
Source Database
DisGeNET
Description
We report 2 novel TNNI3 missense mutations, Lys36Gln and Asn185Lys, each associated with severe and early onset familial DCM.
Pubmed
19590045
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00345279946692324
Year of publication
2009
Drugs